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PubMed COVID-19 Clinical Care

12991 - 13000 of 44979 results found

Molecular Design of Novel Inhibitor by TargetingIL-6Rα using Combined Pharmacophore and Experimentally Verified Plant Products with Scaffold-Hopping Techniques: A Dual Therapeutic Strategy for COVID-19 and Cancer

Date
Wednesday, November 15, 2023 - 4:00 AM
Description
The IL-6/IL-6R/gp130 complex serves as a significant indicator of cytokine release syndrome in COVID-19 and chronic inflammation, increasing the risk of cancer. Therefore, we identified IL-6Rα as a potential target to block gp130 interaction. Notably

Viral infections and pathogenesis of glaucoma: a comprehensive review

Date
Wednesday, November 15, 2023 - 4:00 AM
Description
SUMMARYGlaucoma is a leading cause of irreversible blindness worldwide, caused by the gradual degeneration of retinal ganglion cells and their axons. While glaucoma is primarily considered a genetic and age-related disease, some inflammatory